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Two key treatments do not halt diabetes in people with early signs of the disease, a large study has found. Researchers said the results showed the only way to ensure future health in people at high risk of diabetes is exercise and a healthy diet. Trials in more than 9,000 people also found no reduction in future heart problems in people prescribed two drug treatments compared with dummy pills. In the trial, researchers in the US and UK looked at whether using a drug that lowers blood pressure or a drug which lowers blood sugar could be used to stop diabetes developing in high-risk patients. But the results, from patients in 40 countries, found no great difference in how many people went on to get diabetes when prescribed either drug compared with a dummy pill. Neither did the drugs prevent future heart attacks and strokes, which are dangerous complications of the condition.
Chris Groves
Administration IMD MRC MHU Research Support WIMM
BSc (Hons) Chris Groves - MRC MHU Laboratory Manager
Simon Davis
IMD MRC TIDU Principal Investigators
BSc (Hons), PhD Simon Davis - Professor of Molecular Immunology
Alain Townsend
Emeritus Professors IMD MRC TIDU WIMM
FRS FRCP Alain Townsend - Emeritus Professor of Molecular Immunology
Timothy Rostron
IMD MRC TIDU Research Support
BSc; MSc Timothy Rostron - Sequencing and HLA Typing Laboratory Manager
Jan Rehwinkel
IMD MRC TIDU Principal Investigators
PhD Jan Rehwinkel - Professor of Innate Immunology