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Two key treatments do not halt diabetes in people with early signs of the disease, a large study has found. Researchers said the results showed the only way to ensure future health in people at high risk of diabetes is exercise and a healthy diet. Trials in more than 9,000 people also found no reduction in future heart problems in people prescribed two drug treatments compared with dummy pills. In the trial, researchers in the US and UK looked at whether using a drug that lowers blood pressure or a drug which lowers blood sugar could be used to stop diabetes developing in high-risk patients. But the results, from patients in 40 countries, found no great difference in how many people went on to get diabetes when prescribed either drug compared with a dummy pill. Neither did the drugs prevent future heart attacks and strokes, which are dangerous complications of the condition.
Paul Johnson
OCDEM Principal Investigators
MA MD FRCS (Paed.Surg) FAAP Paul Johnson - Director of Oxford Islet Isolation and Islet Transplant Programmes and Professor of Paediatric Surgery
Peter Rothwell
AMIIC
MD PhD FRCP Peter Rothwell - Founding Director of the Wolfson Centre for the Prevention of Stroke and Dementia and Action Research Professor of Neurology
Parag Gajendragadkar
CVM Researchers
MA, MB BChir, MPhil (Cantab), DPhil (Oxon), MRCP Parag Gajendragadkar - Senior Clinical Fellow in Electrophysiology
Timothy Betts
CVM Principal Investigators
MD, MBChB, FRCP Timothy Betts - Associate Professor of Cardiovascular Medicine
Elizabeth Ormondroyd
CVM Principal Investigators
PhD; MSc Genetic Counselling Elizabeth Ormondroyd - Principal Investigator in RDM; Senior researcher; Genetic counsellor
Reshma Ramracheya
OCDEM Visitors and Affiliates
BSc (Hons), PhD Reshma Ramracheya - Visiting Scientist
Naveed Akbar
CVM Principal Investigators
BSc (Hons), MSc, PhD, FHEA Naveed Akbar - ASSOCIATE PROFESSOR OF CARDIOVASCULAR SCIENCE
Stefan Piechnik
CVM OCMR Principal Investigators
DSc, PhD, MScEE, FSCMR Stefan Piechnik - Professor of Biomedical Imaging
Betty Raman
CVM OCMR Principal Investigators
MBBS DPhil FESC FRACP Betty Raman - Associate Professor of Cardiovascular Medicine