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Photomicroph of cardiac muscle tissue

The APSselect award is given on a monthly basis by The American Journal of Physiology to the top 10 or 11 articles which are selected from their issues of the previous month. 

Dr Robinson won the award for his article on dilated cardiomyopathy (DCM), a frequently occurring cardiac disorder with a degree of genetic inheritance. Dr Robinson says "We have found that DCM mutations in proteins that regulate the contractile machinery cause alterations to contraction, calcium-handling, and some new signaling pathways that provide stimuli for disease development. We have used guinea pig cells that recapitulate human calcium-handling and introduced the mutations using adenovirus gene transduction to look at the initial triggers of disease before remodelling."

You can hear more on the special AJP Heart Circulation podcast featuring Dr Robinson being interviewed by Associate Editor Crystal Ripplinger. 

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Publishing a paper? Just won an award? Get in touch with communications@rdm.ox.ac.uk