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Risk Assessments

Current Departmental risk assessments for research under the Genetically Modified Organisms (Contained Use) Regulations 2000 can be accessed via the Novell shered drive 'NDCLS/Safety'

Ref-Code Class Supervisor Project Title
CBGM1 1 Hyde Expression of human and other mammalian genes encoding the multidrug resistance, cystic fibrosis proteins and viral proteins in baculovirus insect cell systems and mammalian cells
CBGM2 1 Hyde Expression of bacterial genes in Salmonella typhimurium LT2
CBGM3 1 Hyde Expression of human p-glycoprotein and its mutants in yeast
CBGM4 1 Hyde Expression of mammalian multidrug resistance, cystic fibrosis and related genes in E.coli
CBGM9 1 Hyde Expression of bacterial proteins in E.coli
CBGM13 1 Hyde Expression of mammalian genes in mammalian cells using adenoviral vectors
CBGM14 1 Hyde Expression of mammalian, viral and marker genes in rodents
CBGM15 1 Hyde Breeding of CFTR knockout mice
CBGM16 2 Hyde The use of retroviral and lentiviral vectors to facilitate transgene expression and/or gene silencing by RNA interference in mammalian cell and tissue culture systems
CBGM17 1 Hyde Minimal lentiviral vectors
CBGM18 1 Hyde Recombinant adeno-associated virus vectors
CS1 1 Banham/Pulford Expression in bacteria of human proteins involved in chromosomal tranlocations
CS2 1 Gatter Expression in bacteria of human proteins associated with angiogenesis
CS3 1 Banham/Pulford Expression in bacteria of human proteins involved in apoptosis
CS4 1 Banham/Pulford Expression in bacteria of human ALK related proteins involved in chromosomal translocations
CS6 1 Banham/Pulford Expression cloning of human genes involved in translocations, apoptosis and transcription factors from lambda libraries
CS7 1 Banham/Pulford DNA preparation and cloning of human genes related to chromosomal translocations, apoptosis and transcription factors
CS9 1 Boultwood Identification of cDNA's mapping to human chromosome 5q using recombinant E.coli plasmids
CS14 1 Banham/Pulford Study of an in vitro immune response to anaplastic lymphoma kinase (ALK) using recombinant modified virus Ankara (MVA)
CS15 1 Banham/Pulford Expression of cytoplasmic region of ALK protein in modified virus Ankara (MVA)
CS17 1 Banham Expression in bacteria of human MHC-I and associated proteins
CS18 1 Banham Expression of human genes in E. coli
CS19 1 Banham Expression and silencing of mammalian genes and use of standard laboratory reporter genes in mammalian cells
PB5 1 Crook Sequence analysis of the whole Haemophilus influenza conjugative resistance plasmid
PB7 1 Crook Investigation and function and regulation of genes present on p1056 and related large Haemophilus resistance plasmids
PB8 1 Crook In vitro transcription of hepatitis delta virus (HDV) RNA (mutant) for use as a RT-PCR control
PB9 1 Crook Cloning of PCR amplicons generated from viral diagnostic tests into the vector pGemT easy (Promega), for use as positive controls in the same viral diagnosis tests
PB10 1 Crook Cloning of non-infective non-circularised viroid cDNA fragment in a plasmid for use as a RT-PCR control
PB11 1 Crook Random insertion mutagenesis of Streptococcus uberis
PB12 1 Crook Cloning and expression of extra-cytoplasmic proteins or derivatives thereof, from Streptococcus uberis in Escherichia coli