Obesity is a major determinant of the association of C-reactive protein levels and the metabolic syndrome in type 2 diabetes.

Kahn SE., Zinman B., Haffner SM., O'Neill MC., Kravitz BG., Yu D., Freed MI., Herman WH., Holman RR., Jones NP., Lachin JM., Viberti GC., ADOPT Study Group .

The inflammatory factor C-reactive protein (CRP) and the fibrinolytic variables fibrinogen and plasminogen activator-1 (PAI-1) are associated with long-term cardiovascular morbidity. To determine the contribution of body adiposity (BMI), insulin sensitivity (homeostasis model assessment of insulin resistance [HOMA-IR], and glycemia (HbA(1c) [A1C]) to the levels of these inflammatory and fibrinolytic variables in recently diagnosed (

DOI

10.2337/db06-0116

Type

Journal article

Publication Date

2006-08-01T00:00:00+00:00

Volume

55

Pages

2357 - 2364

Total pages

7

Keywords

Adiposity, Blood Glucose, Body Mass Index, C-Reactive Protein, Diabetes Mellitus, Type 2, Fasting, Female, Fibrinogen, Fibrinolysis, Glycated Hemoglobin, Homeostasis, Humans, Insulin Resistance, Male, Metabolic Syndrome, Middle Aged, Obesity, Plasminogen Activator Inhibitor 1

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