Oxford Centre for Diabetes, Endocrinology and Metabolism

OCDEM is a pioneering centre that combines clinical care, research and education in diabetes, endocrine and metabolic diseases. By promoting world-class research, we aim to enhance understanding of these diseases and to accelerate the search for new treatments and cures.

Head of OCDEM

David Ray

Professor of Endocrinology, Head of OCDEM, and Co-Director Sir Jules Thorn Sleep and Circadian Neuroscience Institute

david.ray@ocdem.ox.ac.uk

History

Read about the beginnings of our centre.

Find out more

Latest publications

Impact of chronic hyperglycaemia on the coronary microcirculation – benefits of targeting IL-36 and diet reversal
HODSON D., (2025), Basic Research in Cardiology
Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events.
Wightman H. et al, (2025), PLoS Med, 22
Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?
Dissanayake HA. et al, (2025), Clin Endocrinol (Oxf)
Glucocorticoid-induced hyperglycaemia in hospitalised adults: A matched cohort study (2013-2023).
Golubic R. et al, (2025), Diabetes Obes Metab

Patient undergoing a DEXA scan

OCDEM is one of the largest dedicated research centres in diabetes, endocrinology and metabolism in Europe. Led by Professor David Ray, our work spans the spectrum of basic, translational and patient-orientated research. We are closely integrated with excellent clinical care for patients with diabetes, metabolic and endocrine conditions.

Areas of strength

Type 2 diabetes including genomics, islet biology and function, novel therapeutics and large-scale clinical trials providing evidence for best practise
Human integrative metabolic physiology
Endocrine disorders such as glucocorticoid action, pituitary tumours and calcium homeostasis