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AIMS: The age-thrombus burden-index of microcirculatory resistance (ATI) score is a diagnostic tool able to predict suboptimal myocardial reperfusion before stenting, in patients with ST-elevation myocardial infarction (STEMI). We aimed to validate the ATI score against cardiac magnetic resonance imaging (cMRI). METHODS AND RESULTS: The ATI score was calculated prospectively in 80 STEMI patients. cMRI was performed within 48 hours in all patients and in 50 patients at six-month follow-up to assess the extent of infarct size (IS%) and microvascular obstruction (MVO%). The ATI score was calculated using age (>50=1 point), pre-stenting index of microcirculatory resistance (IMR) (>40 and <100=1 point; ≥100=2 points) and angiographic thrombus score (4=1 point; 5=3 points). ATI score was closely related to final IS% (ATI.

Original publication

DOI

10.4244/EIJ-D-17-00367

Type

Journal article

Journal

EuroIntervention

Publication Date

20/10/2017

Volume

13

Pages

935 - 943

Keywords

Aged, Aged, 80 and over, Coronary Circulation, Female, Humans, Magnetic Resonance Imaging, Male, Microcirculation, Middle Aged, Myocardial Infarction, Myocardial Reperfusion, Percutaneous Coronary Intervention, ST Elevation Myocardial Infarction, Treatment Outcome